Education & Training, General Information, Hematology, Pathology

Test Updates: Complete Blood Count (CBC) and Pathology Consult, Hematology Smear Review

Effective October 3, 2023, the following changes to CBC and Blood Smear testing will be made at Corewell Health Reference Lab – West:

What is Changing:

Complete Blood Count with Manual Differential [LAB2111032] will be inactivated

Replacement test is Complete Blood Count (CBC) w/Differential [LAB293]

See blog post: Complete Blood Count (CBC) with Manual Differential Order Discontinuation for more information.

Manual Differential, Blood [LAB815] will be made a lab only orderable.

 

Pathology Consult Hematology (West and South) [LAB1231502] will be available to order.

• Pathology Consult Hematology (West and South) [LAB1231502] is a lab panel which will include CBC w/Diff [LAB293] and Pathology Consult, Hematology Smear Review [LAB1231501]

Pathology Consult, Hematology Smear Review [LAB1231501] is a component test and should only be ordered if a CBC w/diff has been resulted and a slide has been created.

A new order question will need to be answered in order to order. “What is the CBC abnormality you are concerned about?”

In Epic results for Pathology Review, Blood Smear for Consult will now flow to the “Labs” section instead of the “Notes” section. Interfaced results should flow back to the provider’s EMR. 

Pathologist Review Smear [LAB7550] will be made a lab only orderable.

 

PROVIDER WORKFLOW OPTIONS

If a provider orders CBC w/Diff [LAB293] – Recommended

If CBC w/Diff meets criteria for a review by a Hematopathologist (see chart below), the Lab will order a Pathologist Review Peripheral Smear [LAB7550]

If CBC does not meet criteria, no further testing will be performed.

If a provider orders Pathology Consult Hematology (West and South) [LAB1231502]

A CBC w/Diff will be performed and Pathology Consult, Hematology Smear Review will be reviewed by the Hematopathologist.

If a CBC has been ordered in the last 24 hours, it will add the Pathology Consult, Hematology Smear Review onto the CBC.

 

Pre-established criteria for tech initiated pathologist review are as follows:

Component

Criteria

White Blood Cell (WBC) Criteria

WBC < 1.5 x 103/µL  or  > 30.0 x 103/µL
Absolute Basophil Count (BASOAB) >0.50 x 103/µL
Absolute Eosinophil Count (EOSIAB) >2.00 x 103/µL
Absolute Lymphocyte Count (LYMPAB) >5.0 x 103/µL
Absolute Monocyte Count (MONOAB) >2.0 x 103/µL and >30% on differential
Absolute Neutrophil Count (NEUTAB) <0.50 x 103/µL
Blasts or Immature cells 1st time or unexpected
Abnormal Lymphocytes Example: circulating lymphoma cells, hairy cells, villous lymphocytes

Red Blood Cell (RBC) Criteria

Hemoglobin <7.0 g/dL or >19.0 g/dL
MCV <60.0 fL or >115.0 fL
Nucleated Red Cell Count (NRBC) >10 in 100 cell manual differential (not newborn)
Schistocytes, spherocytes, teardrops on erythrocytes Moderate or many

Platelet Criteria

Platelets <50 x 103/µL (all ages), >700 x 103/µL (adults), >899 x 103/µL (<18 years of age)
Circulating Megakaryocytes Present

Other Peripheral Blood or Body Fluid Smear Criteria

Presence of any: Unidentified Cells, Malignant Cells, Lymphoma Cells, Blasts or immature cells that might be blasts, Organisms
Anything abnormal, suspicious, or with a significant change from previous slides that the technologist believes should be reviewed by a pathologist.

 

 

For questions or inquiries please use the “Contact Us” link above.

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