Starting November 1, 2020, the Lyme Total Antibody test will temporarily not be performed in-house and will be sent out to the Mayo Clinic Laboratories using the Lyme Disease Serology, Serum. This is due to the backorder of reagents from the vendor until approximately January 2021.
Lyme Disease Serology, Serum is available to order in Epic. Lyme Total Antibody will still be available to order, however, when the specimen arrives to the laboratory the order will be switched to the Lyme Disease Serology, Serum.
Similarly, to the current in-house test, the Mayo assay is also a Lyme total antibody assay, detecting both IgG and IgM antibodies, with the same specimen type as the in-house test. However, test turn-around-times may be increased.
Lastly, this change will have no effect on the reflexing of positive samples to the confirmatory Lyme Disease Antibody, Immunoblot, Serum.
Due to low volume, Osteocalcin Blood Level will be discontinued. Recommended alternative test for bone formation evaluation is Procollagen I Intact N-Terminal, Serum (P1NP).
For Hemoglobin A1c testing, Mayo Clinic Laboratory has switched to an Ion-Exchange High-Performance Liquid Chromatography (HPLC) method (Bio-RAD D100) which is the same method of A1c testing used at Spectrum Health Regional Laboratory. They no longer offer the alternative method, boronate affinity chromatography, for A1c testing.
When A1c cannot be determined due to interferences that affect the Bio-RAD 100 method, measurement of serum fructosamine is recommended (Mayo test FRUCT).
Effective January 1, 2019, Spectrum Health Regional Laboratory will no longer offer Magnesium, Red Blood Cell [LAB104] as an option for send out testing. This testing will no longer be available through Spectrum Health’s primary reference laboratory, Mayo Clinic Laboratories. This test will become obsolete on January 7, 2019, due to limited clinical utility.