Browsing Tag

Infectious Disease

General Information, Microbiology, Referral/Sendouts, Test Utilization

Obsoletion of Mayo Send-Out Test Influenza Virus A/B Antibodies, IgG and IgM

As of October 29, 2020, the following send-out tests will be will become obsoleted due to lack of clinical utility:

SFLA Influenza Virus A Antibodies, IgG and IgM (Separate Determinations), Serum [LAB802]

SFLB Influenza Virus B Antibodies, IgG and IgM (Separate Determinations), Serum [LAB803]

For diagnosis of acute Influenza infection the following molecular tests are recommended:

Influenza A/B PCR [LAB3255]

Influenza A/B Rapid [LAB9240]**

Influenza A/B Rapid, Influenza A/B PCR if Negative [LAB2111530]**

**Available only at regionals and during times of high flu incidence Continue Reading

Immunochemistry

New Test: COVID-19 IgG Antibody – Serology test

Effective May 18, 2020, Spectrum Health Regional Laboratory is pleased to be offering in-house COVID-19 serology testing, with initial availability 1,000 tests per day.

 

What is Serology Testing?

•  Serology testing measures the body’s immune response to COVID-19 infection in the form of antibody production against the SARS-CoV-2 virus.

•  There is a single COVID-19 serology order available in Epic, however, the Spectrum Health laboratory performs two versions of antibody testing to increase specificity and avoid reporting false positive results. An initial screen will be used to measure total antibody (IgA, IgM, and IgG), and positives will be confirmed by a second method that is specific to IgG.

•  Specificity is critical when the expected prevalence in a community is low. This serology testing is not expected to cross-react with other circulating coronaviruses that cause the common cold.

•  A positive IgG result indicates previous infection with COVID-19, but does not indicate immunity or protection against future infection.

•  This test should not be used to detect acute COVID-19 disease. Symptomatic patients suspected to have acute COVID-19 infection should be tested using a molecular assay.

•  Whether positive or negative for the presence of COVID-19 antibodies, serology testing results do not support easing of behaviors such as social distancing, wearing masks, or hand hygiene.

Continue Reading

Microbiology, Test Utilization

Influenza Epidemic Testing Recommendations 2018

Influenza is currently widespread throughout the nation at epidemic proportions. During influenza epidemics, clinical assessment predicts the presence of influenza infection virtually as well as laboratory testing. Therefore, it is no longer necessary to perform viral testing on ambulatory patients who present with illness consistent with influenza before beginning antiviral treatment. Antiviral treatment for Influenza should be started as soon as possible to have a beneficial effect.

Shortages of supplies and medications frequently occur during Influenza epidemics. However, diagnosis of specific viral respiratory infection remains important for hospitalized patients.

Please follow the current recommendations:

  • Limit availability of viral transport media at ambulatory sites.
  • Emergency departments are to limit viral respiratory testing to patients expected to be admitted.
  • Do not perform testing for test of cure.

Thank you for your support during this time. Please direct any questions to Laboratory Services via the “contact us” link above.