Browsing Category

Flow Cytometry

Advanced Technology Laboratory, Flow Cytometry

Oxidative Burst by Flow Cytometry Update

Effective immediately, Oxidative Burst by Flow Cytometry (#LAB2111414) will no longer require submission of the biological mother’s sample. An adult control specimen will still be required along with the patient’s specimen. For more information on specimen collection, please visit the Laboratory Catalog.

Questions may be directed to the Flow Cytometry Laboratory using the “Contact Us” link above.

Advanced Technology Laboratory, Flow Cytometry, General Information

PNH Flow Cytometry Test Results

High sensitivity flow cytometry testing for paroxysmal nocturnal hemoglobinuria (PNH) is a test done on patient’s peripheral blood to screen for the presence or absence of PNH clones and/or to follow PNH clonal populations.  The lower limit of detection of a PNH clone for the Spectrum Health laboratory has been validated as 0.01% (1:10,000) for red cells, 0.01% (1:10,000) for granulocytes and 0.1% for monocytes (1:1000).

The results from PNH flow cytometry testing can guide the clinical team in classifying a patient’s disease appropriately, analyzing the risk of disease progression, and choosing appropriate testing to monitor response to treatment. Therefore, the PNH flow cytometry test result will now include a pathologist’s interpretation based on the new recommendations given in Updated ICCS/ESCCA Consensus Guidelines for the Clinical Utility of Testing for GPI-Anchor Deficient Clones in Paroxysmal Nocturnal Hemoglobinuria (PNH) and other Bone Marrow Disorders (Accepted article by Dezern and Borowitz, doi: 10.1002/cyto.b.21608).

Advanced Technology Laboratory, Cytogenetics, Flow Cytometry, General Information, Molecular Diagnostics

Advanced Technology Laboratory plays an important role in Oncology

Spectrum Health Regional Laboratory (SHRL) was featured on EightWest on WOOD TV8 on Tuesday, August 30, 2016. Dr. Stephanie F. Williams, Division Chief of Spectrum Health Adult Bone and Marrow Transplant, and Kim Collison, Director of Laboratory Services, talk about the importance and benefits of having SHRL’s Advanced Technology Laboratory right here in West Michigan.

The Advanced Technology Laboratory is “extremely important, particularly for patients with certain cancers…”

“It helps us to diagnose the patients faster and more accurately; to follow the progress of their disease during the treatments that we give, and even at times to guide us in what is the best treatment for a patient…”

“Within 2 hours we had the answer. We did not have to send that specimen out to another laboratory in another state.”

-Stephanie F. Williams, MD, Division Chief, Spectrum Health Adult Bone and Marrow Transplant