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William Chopp

General Information, Toxicology

Test Update: Cystatin C

Effective Wednesday, December 18, 2019, Cystatin C will change from a sendout reference test performed by Mayo Clinic Laboratories to an in-house test performed by Spectrum Health Regional Laboratory. This test will be performed in the Toxicology Laboratory and will include a new reference range (please see link in Test Information below).

Questions may be directed to Toxicology via the “contact us” link above.

TEST INFORMATION

Cystatin C – Epic Code #LAB3226, Interface #11631, CPT #82610

Education & Training, General Information, Test Utilization

Appropriate Thyroid Peroxidase Antibody Ordering

The most conclusive evidence for using thyroid peroxidase antibody (TPO) is predictive in nature when evaluating possible subclinical hypothyroidism. If this test is positive, hypothyroidism occurs at a rate of 4.3% per year versus 2.6% per year when the antibody is negative. While this scenario does not cover all clinical indications for ordering TPO, there is no definitive evidence that repeat TPO testing provides additional information.1

Based on this information the ordering of TPO within Spectrum Health is being modified. If the test is ordered more than once on a patient, a screen will appear in EPIC indicating the following: “This test should typically only be resulted once per lifetime. The duplicate checking indicates that this patient has already had this testing performed. Please see chart review for results.” This is not a “hard stop” but providers will need to click “Continue” to proceed with the order. Continue Reading

Chemistry, General Information

Reference Range Update: Microalbumin AMR

Spectrum Health Regional Laboratory is adjusting the Microalbumin Analytic Measurement Range (AMR) in order to standardize within the Spectrum Health Hospital System and to align with our vendor’s (Roche Diagnostics) recommendations. The lower limit of the Microalbumin AMR will be changed from 0.50 to 1.20 mg/dL. Results below the AMR will now be reported as < 1.20 mg/dL. The upper limit will remain the same at 444.00 mg/dL. Continue Reading