Due to an unexpected instrument downtime in Chemistry, the following test results will not be reported until end of day Tuesday, May 28th.
Spectrum Health Regional Laboratories will be upgrading the hematology instrumentation to the advanced technology of the Sysmex XN analyzers. This will occur on May 29, 2019, and will lead to a standardized approach to hematology results. Due to this upgrade, the following changes will occur:
- The Retic Count, Automated [LAB296] will be eliminated and replaced with the Reticulocyte count with Reticulocyte Hemoglobin [LAB3500].
- This test includes: RBC count, Retic Absolute, Retic He, Retic Percent and the IRF. The IRF (Immature Reticulocyte Fraction) is an early and sensitive index of erythropoiesis, thus useful in the classification of anemias based on the marrow production (increased in regenerating anemias such as acquired hemolytic anemia or blood loss, and decreased in hyporegenerating anemias such as anemia of chronic disease), the therapeutic management of anemia and in monitoring erythropoietic stimulating agents, and in monitoring for bone marrow and stem cell transplants and response.
- All laboratory sites will now be reflexing and reporting the IPF % and IPF absolute when a platelet count is below 75 x 10^3/uL.
- The Immature Platelet Fraction (IPF) is an indicator of the thrombopoietic activity, providing valuable information in assessing the mechanism of thrombocytopenias. An elevated IPF is observed in thrombocytopenia of peripheral origin caused by excessive consumption of platelets (such as ITP), while thrombocytopenia caused by inadequate platelet production is characterized by a reduced number of immature platelets entering into the circulation.
- All laboratory sites will now be reporting the Nucleated Red Blood Cell (NRBC) count with the CBC (Complete Blood Count, [LAB293], [LAB294], [LAB2111032]) results.
- The Red Blood Cell (RBC) morphology grading will align with the International Society for Laboratory Hematology recommendations.
- CSF cell counts ([LAB2111025], [LAB212]) will be reported as WBC and RBC instead of TNC and RBC.
Questions may be directed to Hematology Department using the “Contact Us” link above.
In both the inpatient and outpatient settings, the laboratory has supplied 24 hour urine containers with preservative such as acetic acid, sodium hydroxide, and boric acid. Upon review of specimen stability requirements, it has been determined that a preservative is not needed prior to collection of most 24 hour urine tests as long as the 24 hour container is kept refrigerated or on ice during the collection period.
Spectrum Health has been informed by Roche Diagnostics that the proprietary reagents used to calibrate our instruments and determine control values for ferritin blood level have been updated to reflect deviation of results leading to low result bias. This may have led to patient results being up to 20% lower than actual ferritin level.
Effective immediately, the OB Magnesium (Mg) reference range has been updated from 1.6 to 2.5 mg/dL to 4.8 to 8.0 mg/dL, to reflect the correct therapeutic range for patients receiving magnesium sulfate therapy. The non-OB magnesium reference range is unchanged.
Please direct questions and inquiries to Dr. Jennifer Stumph via the Contact Us link above.
OB Magnesium, Blood Level – Epic code #LAB3400, Interface code #11703, CPT code #83735
Spectrum Health Regional Laboratory is pleased to announce NGAL as a new in-house test, effective Tuesday, March 5, 2019.
As part of the Choosing Wisely campaign, the American Association of Blood Banks (AABB) released five recommendations for transfusions:
Effective March 1, 2019, H. pylori IgG serologic testing will be discontinued as an orderable test at Spectrum Health Laboratory. This testing is no longer recommended by clinical guidelines.